Anal cancer risk is 28-29 times higher in people with hiv infection, compared with the general population, with no difference between men and women, meta-analyses have shown. Anal cancer risk in people with hiv infection may be higher in current smokers, those with concurrent hpv infection, and those with more advanced hiv infection, a nested case-control study showed. Learn about the risk factors for anal cancer and what you might be able to do to help lower your risk. A risk factor is anything that affects your chance of getting a disease such as cancer. Human papillomavirus examination of squamous cell carcinoma tumor tissues from patients in denmark and sweden showed a high proportion of anal cancers to be positive for the types of hpv that are also associated with high risk of cervical cancer. In another study done, high-risk types of hpv, notably hpv-16, were detected in 84 percent of anal cancer specimens examined. Based on the study in denmark and sweden, parkin estimated that 90 of anal cancers are attributable to hpv. Your risk of developing anal cancer depends on many things, including age and lifestyle factors. Anal cancer is a rare form of cancer that affects the tissues of the anus. We explain what you need to know about its causes and how its diagnosed.
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